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Product Name
APOA1 antibody
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Description
APOA1 Mouse Monoclonal antibody. Positive WB detected in human plasma tissue. Positive IHC detected in human liver cancer tissue. Observed molecular weight by Western-blot: 26-28 kDa
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human; other species not tested.
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Alternative names
Apo AI antibody; ApoA I antibody; APOA1 antibody; apolipoprotein A I antibody; Apolipoprotein A1 antibody
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Isotype
Mouse IgG2b
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Preparation
This antibody was obtained by immunization of APOA1 recombinant protein (Accession Number: NM_000039). Purification method: Protein A purified.
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Clonality
Monoclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:1000-1:10000
IHC: 1:20-1:200
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Validations
human plasma tissue were subjected to SDS PAGE followed by western blot with Catalog No:107061(APOA1 Antibody) at dilution of 1:2000
Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using Catalog No:107061(APOA1 Antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using Catalog No:107061(APOA1 Antibody) at dilution of 1:50 (under 40x lens)
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Background
ApoA1 is a major protein component of high density lipoproteins (HDL) which is associated with reversed cholesterol transport, lipid/cholesterol binding, lecithin/cholesterol acyltransferase (LCAT) activation and specific receptors binding. It is synthesized in the liver and small intestine. Defects of ApoA1 cause low HDL level and systemic non-neuropathic amyloidosis. Serum concentration of ApoA1 is inversely related to the risk of developing atherosclerosis. This antibody was generated against the C-terminal region of human ApoA1.
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