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Product Name
Antithrombin III antibody
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Description
Antithrombin III Mouse Monoclonal antibody. Positive WB detected in L02 cells, human brain tissue, human testis tissue, rat brain tissue. Observed molecular weight by Western-blot: 53 kDa
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Tested applications
ELISA, WB
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Species reactivity
Human, Mouse, Rat; other species not tested.
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Alternative names
Antithrombin antibody; Antithrombin III antibody; AT3 antibody; ATIII antibody; HEPARIN COFACTOR I antibody; Serpin C1 antibody; SERPINC1 antibody
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Isotype
Mouse IgG1
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Preparation
This antibody was obtained by immunization of Antithrombin III recombinant protein (Accession Number: BC022309). Purification method: Protein A purified.
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Clonality
Monoclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
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Validations
L02 cells were subjected to SDS PAGE followed by western blot with Catalog No:107060(SERPINC1 Antibody) at dilution of 1:1000
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Background
SERPINC1, also named Antithrombin III or Antithrombin, is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"