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Product Name
Human SLPI (His Tag) recombinant protein
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Description
Acid-stable proteinase inhibitor with strong affinities for trypsin, chymotrypsin, elastase, and cathepsin G. May prevent elastase-mediated damage to oral and possibly other mucosal tissues.
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Protein name
Antileukoproteinase
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Protein short names
RP23-462O16.7; WAP4; ALK1; MPI; WFDC4; BLPI; ALP; HUSI; HUSI-I; SLPI
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Uniprot ID
P03973
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Gene Name
SLPI; WAP4; WFDC4
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Source/Expression Host
Baculovirus-Insect Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the secreted form of human SLPI (P03973) (Ser 26-Ala 132) was expressed, with a polyhistidine tag at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human SLPI consists of 126 amino acids and predicts a molecular mass of 14 kDa. It migrates as an approximately 19 kDa band in SDS-PAGE under reducing conditions.
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Purity
> 84 % as determined by SDS-PAGE
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Activity
Measured by its ability to inhibit trypsin cleavage of a fluorogenic peptide substrate, Mca-RPKPVE-Nval-WRK (Dnp)-NH2 (Catalog # ES002).
The IC50 value is <4 Nm. -
Validations
Human SLPI Protein (His Tag) SDS-PAGE
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