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Product Name
Anti-Thrombomodulin Rabbit antibody
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Description
Thrombomodulin Rabbit monoclonal antibody
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Tested applications
WB, FC
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Species reactivity
Mouse, Rat
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Alternative names
TM; CD141; AI385582 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: Recombinant protein of mouse Thrombomodulin
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Clonality
Monoclonal
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Formulation
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage instructions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze / thaw cycle.
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Applications
1:1000
1:20
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Validations
Western blot detection of Thrombomodulin in 3T3 cell lysates using Thrombomodulin Rabbit mAb(1:1000 diluted).Predicted band size:62kDa.Observed band size:95kDa.
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Background
Swiss-Prot Acc.P15306.Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"