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Product Name
Anti-Tau Rabbit antibody
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Description
Tau Rabbit monoclonal antibody
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Tested applications
WB, IHC-P, IP
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Species reactivity
Human, Mouse
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Alternative names
TAU; MSTD; PPND; DDPAC; MAPTL; MTBT1; MTBT2; FTDP-17; PPP1R103 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: Recombinant protein of human Tau
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Clonality
Monoclonal
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Formulation
50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage instructions
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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Applications
WB: 1/1000
IHC: 1/100
IP: 1/20
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Validations
Western blot detection of Tau in Rat Brain lysates using Tau Rabbit mAb(1:1000 diluted).Predicted band size:79kDa.Observed band size:50-80kDa.
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Background
Swiss-Prot Acc.P10636.Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"