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Product Name
Anti-Superoxide Dismutase 1 Rabbit antibody
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Description
Superoxide Dismutase 1 Rabbit monoclonal antibody
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Tested applications
WB
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Species reactivity
Human
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Alternative names
ALS; SOD; ALS1; IPOA; hSod1; HEL-S-44; homodimer antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide of human Superoxide Dismutase 1
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Clonality
Monoclonal
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Formulation
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage instructions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze / thaw cycle.
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Applications
1:5000-1:20000
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Validations
Western blot detection of Superoxide Dismutase 1 in K562,Hela cell lysates using Superoxide Dismutase 1 Rabbit mAb(1:1000 diluted).Predicted band size:16kDa.Observed band size:16kDa.
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Background
Swiss-Prot Acc.P00441.Destroys radicals which are normally produced within the cells and which are toxic to biological systems.MiscellaneousThe protein (both wild-type and ALS1 variants) has a tendency to form fibrillar aggregates in the absence of the intramolecular disulfide bond or of bound zinc ions. These aggregates may have cytotoxic effects. Zinc binding promotes dimerization and stabilizes the native form.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"