Anti-Superoxide Dismutase 1 Rabbit antibody

Cat.#: 166974

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Product Information

  • Product Name
    Anti-Superoxide Dismutase 1 Rabbit antibody
  • Documents
  • Description
    Superoxide Dismutase 1 Rabbit polyclonal antibody
  • Tested applications
    WB, IHC-P, ICC/IF, FC
  • Species reactivity
    Human, Rat
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: A synthesized peptide derived from human SOD1
  • Clonality
    Polyclonal
  • Formulation
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage instructions
    Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Applications

    WB: 1/500-1/2000

    IHC: 1/50-1/200

    ICC/IF: 1/50-1/200

    FC: 1/50

  • Validations

    Western blot analysis of CD80 expression in Jurkat cell lysate.

    Western blot analysis of CD80 expression in Jurkat cell lysate.

  • Background
    Swiss-Prot Acc.P00441.SOD1, Cu/Zn superoxide dismutase, is a major antioxidant enzyme that catalyzes the conversion of superoxide anion to hydrogen peroxide and molecular oxygen. The mechanism by which mutant SOD1 induces the neurodegeneration observed in ALS is still unclear. Mutant SOD1 proteins become misfolded and consequently oligomerize into high molecular weight species that aggregate and end up in proteinaceous inclusions.
  • References

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"