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Product Name
Anti-SIRT6 (6C9) Mouse antibody
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Description
SIRT6 (6C9) Mouse monoclonal antibody
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Tested applications
WB, ICC/IF, IP
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Species reactivity
Human, Mouse, Rat, Monkey
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Alternative names
2810449N18Rik;AI043036;Mono ADP ribosyltransferase sirtuin 6;NAD-dependent protein deacetylase sirtuin-6;Regulatory protein SIR2 homolog 6;Regulatory protein SIR2 homolog;SIR2 like 6;SIR2 like protein 6;Sir2 related protein type 6;SIR2-like protein 6;SIR2 antibody
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Isotype
Mouse IgG1
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Preparation
Antigen: Purified recombinant human SIRT6 protein expressed in E.coli.
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Clonality
Monoclonal
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Formulation
PBS(pH 7.4) containing with 0.03% Proclin300 and 50% glycerol.
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Storage instructions
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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Applications
WB: 1/500
;ICC: 1/100
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Validations
Immunofluorescent analysis of Hela cells fixed fixed by 4% paraformaldehyde and using SIRT6 mouse mAb (dilution 1:100).
Immunoprecipitation analysis of Hela cell lysates using SIRT6 mouse mAb.
Western blot analysis of extracts from Jurkat,MCF7,HCT116,K562,COS7,C2C12,3T3 and Hela cell lysates using SIRT6 mouse mAb (1:500 diluted).Predicted band size:42,36KDa.Observed band size:42,36KDa.
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Background
Swiss-Prot Acc.Q8N6T7.The Silent Information Regulator (Sir2) family of genes is a highly conserved group of genes that encode nicotinamide adenine dinucleotide (NAD)-dependent protein deacetylases, also known as class III histone deacetylases. SirT6, a mammalian homolog of Sir2, is a nuclear, chromatin-associated protein that promotes the normal maintenance of genome integrity mediated by the base excision repair (BER) pathway.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"