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Product Name
Anti-SHP1 Rabbit antibody
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Description
SHP1 Rabbit monoclonal antibody
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Tested applications
WB, IHC-P, ICC/IF, FC
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Species reactivity
Human
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Alternative names
HCP; HCPH; SHP1; SHP-1; HPTP1C; PTP-1C; SHP-1L; SH-PTP1 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide of human SHP1
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Clonality
Monoclonal
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Formulation
50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage instructions
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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Applications
WB: 1/1000-1/5000
IHC: 1/200-1/500
ICC/IF: 1/50-1/200
FC: 1/20
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Validations
Western blot detection of SHP1 in Jurkat cell lysates using SHP1 Rabbit mAb(1:500 diluted).Predicted band size:68kDa.Observed band size:68kDa.
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Background
Swiss-Prot Acc.P29350.Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation. Plays a key role in hematopoiesis.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"