-
Product Name
Anti-SHP1 (2B7) Mouse antibody
- Documents
-
Description
SHP1 (2B7) Mouse monoclonal antibody
-
Tested applications
WB, IP
-
Species reactivity
Human
-
Alternative names
70 kda SHP1L protein ; 70Z-SHP ; EC 3.1.3.48 ; HCP ; HCPH ; Hematopoietic cell phosphatase ; Hematopoietic cell protein tyrosine phosphatase ; Hematopoietic cell protein-tyrosine phosphatase ; HPTP1C ; Protein tyrosine phosphatase 1C ; Protein tyrosine ph antibody
-
Isotype
Mouse IgG2a
-
Preparation
Antigen: Purified recombinant human SHP-1 protein fragments expressed in E.coli.
-
Clonality
Monoclonal
-
Formulation
Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.03% Proclin300 and 50% glycerol.
-
Storage instructions
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
-
Applications
WB: 1/1000
-
Validations
Western blot detection of SHP-1 in Human tonsil,Daudi,Jurkat and Raji cell lysates using SHP-1 mouse mAb (1:1000 diluted).Predicted band size:67KDa.Observed band size:67KDa.
Immunoprecipitation analysis of Raji cell lysates using SHP-1 mouse mAb.
-
Background
Swiss-Prot Acc.P29350.Plays a key role in hematopoiesis. This PTPase activity may directly link growth factor receptors and other signaling proteins through protein-tyrosine phosphorylation. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"