NovoPro
Cart 2
  • Anti-SFRS3 Rabbit antibody

Anti-SFRS3 Rabbit antibody

Cat.#: 168938

Size:

Special Price 441.3 USD

Availability: In Stock
- +

Add to cart to get an online quotation

Product Information

  • Product Name
    Anti-SFRS3 Rabbit antibody
  • Documents
  • Description
    SFRS3 Rabbit monoclonal antibody
  • Tested applications
    WB, IHC-P, ICC/IF, FC
  • Species reactivity
    Human, Mouse, Rat
  • Alternative names
    SFRS3; SRp20 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: A synthetic peptide of human SFRS3
  • Clonality
    Monoclonal antibody
  • Formulation
    50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
  • Storage instructions
    Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Applications

    WB: 1/1000

    IHC: 1/50

    ICC/IF: 1/100

    FC: 1/50

  • Validations

    Western blot detection of SFRS3 in Jurkat,C6,Hela cell lysates using SFRS3 Rabbit mAb(1:1000 diluted).Predicted band size:19kDa.Observed band size:19kDa.

    Western blot detection of SFRS3 in Jurkat,C6,Hela cell lysates using SFRS3 Rabbit mAb(1:1000 diluted).Predicted band size:19kDa.Observed band size:19kDa.

  • Background
    Swiss-Prot Acc.P84103.Splicing factor that specifically promotes exon-inclusion during alternative splicing (PubMed:26876937). Interaction with YTHDC1, a RNA-binding protein that recognizes and binds N6-methyladenosine (m6A)-containing RNAs, promotes recruitment of SRSF3 to its mRNA-binding elements adjacent to m6A sites, leading to exon-inclusion during alternative splicing (PubMed:26876937). Also functions as export adapter involved in mRNA nuclear export such as of histone H2A (PubMed:11336712, PubMed:18364396). Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NXF1 pathway); enhances NXF1-NXT1 RNA-binding activity (PubMed:11336712, PubMed:18364396). RNA-binding is semi-sequence specific (PubMed:17036044).
  • References

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"