Anti-S100 beta Rabbit antibody

Cat.#: 167008

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Product Information

  • Product Name
    Anti-S100 beta Rabbit antibody
  • Documents
  • Description
    S100 beta Rabbit polyclonal antibody
  • Tested applications
    WB, IHC-P, ICC/IF, IP
  • Species reactivity
    Human, Mouse, Rat
  • Alternative names
    NEF; S100; S100-B; S100beta antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: A synthetic peptide of human S100 beta
  • Clonality
    Polyclonal
  • Formulation
    Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
  • Storage instructions
    Store at -20°C. Stable for 12 months from date of receipt.
  • Applications

    WB: 1/1000

    IHC: 1/50-1/200

    ICC/IF: 1/20

    IP: 1/20

  • Validations

    Immunohistochemistry of S100 beta in paraffin-embedded Human breast cancer tissue using S100 beta Rabbit pAb at dilution 1/50

    Immunohistochemistry of S100 beta in paraffin-embedded Human breast cancer tissue using S100 beta Rabbit pAb at dilution 1/50

    Western blot detection of S100 beta in Rat Brain  lysates using S100 beta Rabbit pAb(1:1000 diluted).Predicted band size:11KDa.Observed band size:11KDa.

    Western blot detection of S100 beta in Rat Brain lysates using S100 beta Rabbit pAb(1:1000 diluted).Predicted band size:11KDa.Observed band size:11KDa.

    Western blot detection of S100 beta in Rat Brain lysates using S100 beta Rabbit pAb(1:500 diluted).Predicted band size:11kDa.Observed band size:11kDa.

    Western blot detection of S100 beta in Rat Brain lysates using S100 beta Rabbit pAb(1:500 diluted).Predicted band size:11kDa.Observed band size:11kDa.

  • Background
    Swiss-Prot Acc.P04271.Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"