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Product Name
Anti-RUNX1/2/3 Rabbit antibody
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Description
RUNX1/2/3 Rabbit polyclonal antibody
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Tested applications
WB, IHC-P, ICC/IF, IP, FC
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Species reactivity
Human, Mouse, Rat
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthesized peptide derived from human RUNX1/RUNX2/RUNX3
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Clonality
Polyclonal
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Formulation
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage instructions
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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Applications
WB: 1/500-1/2000
IHC: 1/50-1/200
ICC/IF: 1/50-1/200
IP: 1/50
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Validations
Western blot analysis of RUNX1/RUNX2/RUNX3 expression in MCF7,Hela and Molt-4 cell lysates using RUNX1/RUNX2/RUNX3 antibody at 1/5000 dilution.Predicted band size:51KDa.Observed band size:51KDa.
Western blot analysis of RUNX1/RUNX2/RUNX3 expression in Raji and Jurkat cell lysates using RUNX1/RUNX2/RUNX3 antibody at 1/5000 dilution.Predicted band size:51KDa.Observed band size:51KDa.
Western blot analysis of RUNX1/RUNX2/RUNX3 expression in MOLT4 cell lysate.
Immunohistochemical analysis of paraffin-embedded mouse lung, using RUNX1/RUNX2/RUNX3 Antibody.
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Background
Swiss-Prot Acc.Q01196,Q13761,Q13950.RUNX2 regulates the transcription of various genes including osteopontin, bone sialoprotein, and osteocalcin via binding to the core site of the enhancers or promoters.RUNX3/AML2 is a member of the Runt family of transcription factors. RUNX3 is important for the suppression of cell proliferation in the gastric epithelium, neurogenesis of the dorsal root ganglia, and T cell differentiation.
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