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Product Name
Anti-RRM2 Rabbit antibody
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Description
RRM2 Rabbit monoclonal antibody
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Tested applications
WB, ICC/IF, IP
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Species reactivity
Human
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Alternative names
R2; RR2; RR2M antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: Recombinant protein of human RRM2
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Clonality
Monoclonal
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Formulation
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage instructions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze / thaw cycle.
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Applications
1:1000
1:50
1:20
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Validations
Western blot detection of RRM2 in K562,Hela cell lysates using RRM2 Rabbit mAb(1:1000 diluted).Predicted band size:45kDa.Observed band size:45kDa.
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Background
Swiss-Prot Acc.P31350.Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Inhibits Wnt signaling.MiscellaneousTwo distinct regulatory sites have been defined: the specificity site, which controls substrate specificity, and the activity site which regulates overall catalytic activity. A substrate-binding catalytic site, located on M1, is formed only in the presence of the second subunit M2.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"