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Product Name
Anti-PTGFRN antibody
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Description
Rabbit Polyclonal to Human PTGFRN
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Tested applications
WB
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Species reactivity
Human EWI-F / PTGFRN
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Alternative names
prostaglandin F2 receptor inhibitor antibody; PTGFRN antibody; CD315 antibody; CD9P-1 antibody; EWI-F antibody; FPRP antibody; SMAP-6 antibody; CD9 partner 1 antibody; glu-Trp-Ile EWI motif-containing protein F antibody; prostaglandin F2 receptor negative regulator antibody; prostaglandin F2-alpha receptor regulatory protein antibody; prostaglandin F2-alpha receptor-associated protein antibody; prostaglandin F2 receptor negative regulator antibody; Ptgfrn antibody; DN-358O3.4 antibody; 4833445A08Rik antibody; AU042434 antibody; CD9P-1 antibody; FPRP antibody; Trim45 antibody; prostaglandin F2-alpha receptor regulatory protein antibody; prostaglandin F2-alpha receptor-associated protein antibody; FPRP antibody; CD315 antibody; EWI-F antibody; CD9P-1 antibody; SMAP-6 antibody; FPRP antibody; CD9P-1 antibody; Trim45 antibody; AU042434 antibody; 4833445A08Rik antibody
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Isotype
Rabbit IgG
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Preparation
Produced in rabbits immunized with a synthetic peptide corresponding to the center region of the Human EWI-F / PTGFRN, and purified by antigen affinity chromatography.
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Clonality
Polyclonal
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Formulation
0.2 μm filtered solution in PBS
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Storage instructions
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles. -
Applications
WB: 0.5-5 μg/ml
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Validations
EWI-F / PTGFRN Antibody, Rabbit PAb, Antigen Affinity Purified, Western blot
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Background
EWI-F, also known as PTGFRN, is inversely related to the loss of CD9. Its expression correlates with the metastatic status of hLT (n=55). EWI-F inhibits the binding of prostaglandin F2-alpha (PGF2-alpha) to its specific FP receptor, by decreasing the receptor number rather than the affinity constant. EWI-F expression positively correlates with the metastatic status of hLT, and that the upregulation of EWI-F expression could be one of the mechanisms underlying the loss of CD9 in solid tumours.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"