Anti-PTGFRN antibody

Cat.#: 141601

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Product Information

  • Product Name
    Anti-PTGFRN antibody
  • Documents
  • Description
    Rabbit Polyclonal to Human PTGFRN
  • Tested applications
    WB
  • Species reactivity
    Human EWI-F / PTGFRN
  • Alternative names
    prostaglandin F2 receptor inhibitor antibody; PTGFRN antibody; CD315 antibody; CD9P-1 antibody; EWI-F antibody; FPRP antibody; SMAP-6 antibody; CD9 partner 1 antibody; glu-Trp-Ile EWI motif-containing protein F antibody; prostaglandin F2 receptor negative regulator antibody; prostaglandin F2-alpha receptor regulatory protein antibody; prostaglandin F2-alpha receptor-associated protein antibody; prostaglandin F2 receptor negative regulator antibody; Ptgfrn antibody; DN-358O3.4 antibody; 4833445A08Rik antibody; AU042434 antibody; CD9P-1 antibody; FPRP antibody; Trim45 antibody; prostaglandin F2-alpha receptor regulatory protein antibody; prostaglandin F2-alpha receptor-associated protein antibody; FPRP antibody; CD315 antibody; EWI-F antibody; CD9P-1 antibody; SMAP-6 antibody; FPRP antibody; CD9P-1 antibody; Trim45 antibody; AU042434 antibody; 4833445A08Rik antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Produced in rabbits immunized with a synthetic peptide corresponding to the center region of the Human EWI-F / PTGFRN. The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
  • Clonality
    Polyclonal
  • Formulation
    0.2 μm filtered solution in PBS
  • Storage instructions
    This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
    Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
  • Applications

    WB: 0.5-5 μg/ml

  • Validations

    EWI-F / PTGFRN Antibody, Rabbit PAb, Western blot

    EWI-F / PTGFRN Antibody, Rabbit PAb, Western blot

  • Background
    EWI-F, also known as PTGFRN, is inversely related to the loss of CD9. Its expression correlates with the metastatic status of hLT (n=55). EWI-F inhibits the binding of prostaglandin F2-alpha (PGF2-alpha) to its specific FP receptor, by decreasing the receptor number rather than the affinity constant. EWI-F expression positively correlates with the metastatic status of hLT, and that the upregulation of EWI-F expression could be one of the mechanisms underlying the loss of CD9 in solid tumours.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"