-
Product Name
Anti-PROX1 Rabbit antibody
- Documents
-
Description
PROX1 Rabbit monoclonal antibody
-
Tested applications
WB
-
Species reactivity
Human
-
Isotype
Rabbit IgG
-
Preparation
Antigen: A synthetic peptide of human PROX1
-
Clonality
Monoclonal
-
Formulation
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
-
Storage instructions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze / thaw cycle.
-
Applications
1:1000-1:5000
-
Validations
Western blot detection of PROX1 in C6 cell lysates using PROX1 Rabbit mAb(1:1000 diluted).Predicted band size:83kDa.Observed band size:85kDa.
-
Background
Swiss-Prot Acc.Q92786.Transcription factor involved in developmental processes such as cell fate determination, gene transcriptional regulation and progenitor cell regulation in a number of organs. Plays a critical role in embryonic development and functions as a key regulatory protein in neurogenesis and the development of the heart, eye lens, liver, pancreas and the lymphatic system. Involved in the regulation of the circadian rhythm. Represses: transcription of the retinoid-related orphan receptor RORG, transcriptional activator activity of RORA and RORG and the expression of RORA/G-target genes including core clock components: ARNTL/BMAL1, NPAS2 and CRY1 and metabolic genes: AVPR1A and ELOVL3.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"