Anti-Proteasome subunit alpha type 6 Rabbit antibody

Anti-Proteasome subunit alpha type 6 Rabbit antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

Proteasome subunit alpha type 6 Rabbit monoclonal antibody

WB

Human, Mouse, Rat

Rabbit IgG

Antigen: A synthetic peptide of human Proteasome subunit alpha type 6

Monoclonal

50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA

Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Multiple transcript variants encoding several different isoforms have been found for this gene. A pseudogene has been identified on the Y chromosome. [provided by RefSeq, Aug 2013]