Anti-Proteasome subunit alpha type 6 Rabbit antibody

Anti-Proteasome subunit alpha type 6 Rabbit antibody

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• Material Safety Data Sheets (MSDS)

Proteasome subunit alpha type 6 Rabbit polyclonal antibody

WB, ICC/IF, FC

Human, Mouse, Rat

IOTA; p27K; PROS27 antibody

Rabbit IgG

Antigen: A synthetic peptide of human Proteasome subunit alpha type 6

Polyclonal

Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.

Store at -20°C. Stable for 12 months from date of receipt.

Swiss-Prot Acc.P60900.Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).