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Product Name
Anti-PLN antibody
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Description
Mouse monoclonal antibody to PLN
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Tested applications
WB, IP, IF
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Species reactivity
Human, Mouse, Rat
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Alternative names
PLB antibody; CMD1P antibody; CMH18 antibody
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Isotype
Mouse IgG1
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Preparation
This antigen of this antibody was specific for an epitope mapping between amino acids 7-32 at the n-terminus of phospholamban of human origin.
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Clonality
Monoclonal
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Formulation
Liquid, 1*TBS (pH7.4), 1%BSA. Preservative: 0.05% Sodium Azide.
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Storage instructions
Store at +4℃.
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Applications
WB: 1:100-1:1,000
IP: 1-2 μg per 100-500 μg of total protein(1 ml of cell lysate)
IF: 1:50-1:500
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Validations
Fig1: Western blot analysis of phospholamban expression in mouse heart (A) and human heart (B) tissue extracts.
- Background
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References
- Zhai, J., et al. 2000. Cardiac-specific overexpression of a superinhibitory pentameric phospholamban mutant enhances inhibition of cardiac function in vivo. J. Biol. Chem. 275: 10538-10544.
- Minamisawa, S., et al. 1999. Chronic phospholamban-sarcoplasmic reticulum calcium ATPase interaction is the critical calcium cycling defect in dilated cardiomyopathy. Cell 99: 313-322.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"