Anti-PIM1 Rabbit antibody

Cat.#: 167774

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Product Information

  • Product Name
    Anti-PIM1 Rabbit antibody
  • Documents
  • Description
    PIM1 Rabbit monoclonal antibody
  • Tested applications
    WB, IHC-P, ICC/IF, FC
  • Species reactivity
    Human, Mouse
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: A synthetic peptide of human PIM1
  • Clonality
    Monoclonal
  • Formulation
    50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA
  • Storage instructions
    Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Applications

    WB: 1/2000-1/10000

    IHC: 1/20-1/50

    ICC/IF: 1/20-1/100

    FC: 1/20

  • Validations

    Western blot detection of PIM1 in Hela,A549,HL-60 cell lysates using PIM1 Rabbit mAb(1:1000 diluted).Predicted band size:45kDa.Observed band size:34kDa.

    Western blot detection of PIM1 in Hela,A549,HL-60 cell lysates using PIM1 Rabbit mAb(1:1000 diluted).Predicted band size:45kDa.Observed band size:34kDa.

  • Background
    The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons (PMIDs:16186805, 1825810).[provided by RefSeq, Aug 2011]

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"