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Product Name
Anti-Phospho-NFAT2 (Ser237) Rabbit antibody
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Description
Phospho-NFAT2 (Ser237) Rabbit polyclonal antibody
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Tested applications
WB, FC
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Species reactivity
Human
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Alternative names
NFAT2; NFATc; NF-ATC; NF-ATc1.2 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic phosphopeptide corresponding to residues surrounding Ser237 of human NFAT2
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Clonality
Polyclonal
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Formulation
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage instructions
Store at -20°C. Stable for 12 months from date of receipt.
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Applications
WB: 1/1000
FC: 1/50
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Validations
Western blot detection of NFAT2 (Phospho-Ser237) in K562,3T3 cell lysates using NFAT2 (Phospho-Ser237) Rabbit pAb(1:1000 diluted).Predicted band size:101kDa.Observed band size:101kDa.
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Background
Swiss-Prot Acc.O95644.Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 or IL-4 gene transcription. Also controls gene expression in embryonic cardiac cells. Could regulate not only the activation and proliferation but also the differentiation and programmed death of T-lymphocytes as well as lymphoid and non-lymphoid cells (PubMed:10358178). Required for osteoclastogenesis and regulates many genes important for osteoclast differentiation and function .
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"