Anti-Phospho-Glutamate Receptor 1 (AMPA subtype) (Ser845) Rabbit antibody
Phospho-Glutamate Receptor 1 (AMPA subtype) (Ser845) Rabbit monoclonal antibody
Human, Mouse, Rat
GLUH1; GLUR1; GLURA; GluA1; HBGR1 antibody
Antigen: A synthetic phosphopeptide corresponding to residues surrounding Ser845 of human AMPA Receptor 1 (GluA1)
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze / thaw cycle.
Western blot detection of Phospho-Glutamate Receptor 1 (AMPA subtype) (Ser845) in C6 cell lysates using Phospho-Glutamate Receptor 1 (AMPA subtype) (Ser845) Rabbit mAb(1:1000 diluted).Predicted band size:102kDa.Observed band size:102kDa.
Swiss-Prot Acc.P42261.Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.
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