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  • Anti-Phospho-Glutamate Receptor 1 (AMPA subtype) (Ser845) Rabbit antibody

Anti-Phospho-Glutamate Receptor 1 (AMPA subtype) (Ser845) Rabbit antibody

Cat.#: 168864

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Product Information

  • Product Name
    Anti-Phospho-Glutamate Receptor 1 (AMPA subtype) (Ser845) Rabbit antibody
  • Documents
  • Description
    Phospho-Glutamate Receptor 1 (AMPA subtype) (Ser845) Rabbit monoclonal antibody
  • Tested applications
    WB
  • Species reactivity
    Human, Mouse, Rat
  • Alternative names
    GLUH1; GLUR1; GLURA; GluA1; HBGR1 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: A synthetic phosphopeptide corresponding to residues surrounding Ser845 of human AMPA Receptor 1 (GluA1)
  • Clonality
    Monoclonal antibody
  • Formulation
    Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
  • Storage instructions
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze / thaw cycle.
  • Applications

    1:1000

  • Validations

    Western blot detection of Phospho-Glutamate Receptor 1 (AMPA subtype) (Ser845) in C6 cell lysates using Phospho-Glutamate Receptor 1 (AMPA subtype) (Ser845) Rabbit mAb(1:1000 diluted).Predicted band size:102kDa.Observed band size:102kDa.

    Western blot detection of Phospho-Glutamate Receptor 1 (AMPA subtype) (Ser845) in C6 cell lysates using Phospho-Glutamate Receptor 1 (AMPA subtype) (Ser845) Rabbit mAb(1:1000 diluted).Predicted band size:102kDa.Observed band size:102kDa.

  • Background
    Swiss-Prot Acc.P42261.Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.
  • References

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"