-
Product Name
Anti-PDRG1 / C20orf126 antibody
- Documents
-
Description
Rabbit polyclonal to PDRG1 / C20orf126
-
Tested applications
ELISA, IHC-P
-
Species reactivity
Human PDRG1 / C20orf126
-
Alternative names
p53 and DNA-damage regulated 1 antibody; PDRG1 antibody; RP1-310O13.8 antibody; C20orf126 antibody; PDRG antibody; p53 and DNA damage-regulated protein 1 antibody; p53 and DNA damage regulated 1 antibody; Pdrg1 antibody; RP23-88J10.1 antibody; 1110004D19Rik antibody; AU020945 antibody; AV006589 antibody; Pdrg antibody; p53 and DNA damage-regulated protein 1 antibody; PDRG antibody; C20orf126 antibody; Pdrg antibody; AU020945 antibody; AV006589 antibody; 1110004D19Rik antibody
- Immunogen
-
Isotype
Rabbit IgG
-
Preparation
Produced in rabbits immunized with purified, recombinant Human PDRG1 / C20orf126 (rh PDRG1 / C20orf126; Q9NUG6; Met1-Gly133). PDRG1 / C20orf126 specific IgG was purified by Human PDRG1 / C20orf126 affinity chromatography.
-
Clonality
Polyclonal
-
Formulation
0.2 μm filtered solution in PBS
-
Storage instructions
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles. -
Applications
ELISA:0.1-0.2 μg/mL
This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human PDRG1 / C20orf126. The detection limit for Human PDRG1 / C20orf126 is < 0.039 ng/well.
IHC-P: 0.05-0.5 μg/ml
-
Validations
PDRG1 / C20orf126 Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry
PDRG1 / C20orf126 Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry
PDRG1 / C20orf126 Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry
-
Background
PDRG1, also known as C20orf126, belongs to the prefoldin subunit beta family. It is predominantly expressed in normal testis and exhibits reduced but detectable expression in other organs. PDRG1 may play a role in chaperone-mediated protein folding. PDRG1 is overexpressed in tumors relative to normal tissues. Its expression is upregulated in multiple malignancies including cancers of the colon, rectum, ovary, lung, stomach, breast and uterus when compared to their respective matched normal tissues. Thus PDRG1 is a high-value novel tumor marker that could play a role in cancer development and/or progression.
-
References
- Kim W. et al., 2011, Mol Cell. 44 (2): 325-40.
- Havugimana PC. et al., 2012, Cell. 150 (5): 1068-81.
- Jiang L. et al., 2011, Cancer Biol Ther. 11 (6): 567-73.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"