Anti-PDE1C antibody

Anti-PDE1C antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

Rabbit Polyclonal to Human PDE1C

IHC-P

Human PDE1C

5'-cyclic nucleotide phosphodiesterase 1C antibody; calcium/calmodulin-dependent 3' antibody; calcium/calmodulin-dependent 3' antibody; cam-PDE 1C antibody; cam-PDE 1C antibody; Hcam3 antibody; hCam-3 antibody; Human 3' antibody; 5' cyclic nucleotide phosphodiesterase (HSPDE1C1A) antibody; 5'-cyclic nucleotide phosphodiesterase 1C antibody; Hcam3 antibody; hCam-3 antibody; cam-PDE1C antibody

Rabbit IgG

Produced in rabbits immunized with purified, recombinant Human PDE1C . PDE1C specific IgG was purified by Human PDE1C affinity chromatography.

Polyclonal

0.2 μm filtered solution in PBS

This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

PDE1C belongs to the cyclic nucleotide phosphodiesterase family, PDE1 subfamily. Phosphodiesterases (PDEs) are a family of related phosphohydrolyases that selectively catalyze the hydrolysis of 3' cyclic phosphate bonds in adenosine and/or guanine 3',5' cyclic monophosphate (cAMP and/or cGMP). They regulate the cellular levels, localization and duration of action of these second messengers by controlling the rate of their degradation. PDEs are expressed ubiquitously, with each subtype having a specific tissue distribution. These enzymes are involved in many signal transduction pathways and their functions include vascular smooth muscle proliferation and contraction, cardiac contractility, platelet aggregation, hormone secretion, immune cell activation, and they are involved in learning and memory. PDE1C has a high affinity for both cAMP and cGMP. It is expressed in several tissues, including brain and heart. As a cyclic nucleotide phosphodiesterase, PDE1C has a dual-specificity for the second messengers cAMP and cGMP.