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Product Name
Anti-NUR77 Rabbit antibody
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Description
NUR77 Rabbit monoclonal antibody
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Tested applications
WB
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Species reactivity
Human, Mouse, Rat
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Alternative names
HMR; N10; TR3; NP10; GFRP1; NAK-1; NGFIB; NUR77 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide of human NUR77
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Clonality
Monoclonal
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Formulation
50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage instructions
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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Applications
WB: 1/1000-1/5000
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Validations
Western blot detection of NUR77 in Rat Brain lysates using NUR77 Rabbit mAb(1:500 diluted).Predicted band size:65kDa.Observed band size:65kDa.
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Background
Swiss-Prot Acc.P22736.Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3' . May inhibit NF-kappa-B transactivation of IL2. Participates in energy homeostasis by sequestrating the kinase STK11 in the nucleus, thereby attenuating cytoplasmic AMPK activation. Plays a role in the vascular response to injury .
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"