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Product Name
Anti-NTRK1 antibody
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Description
Rabbit monoclonal antibody to NTRK1
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Tested applications
WB, ICC, IHC-P
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Species reactivity
Human, Mouse, Rat
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Alternative names
MTC antibody; TRK antibody; TRK1 antibody; TRKA antibody; Trk-A antibody; p140-TrkA antibody
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Isotype
Rabbit IgG
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Preparation
This antigen of this antibody was recombinant protein.
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Clonality
Monoclonal
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Formulation
Liquid, 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Storage instructions
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
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Applications
WB: 1:1,000-1:5,000
ICC: 1:50-1:200
IHC-P: 1:50-1:200
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Validations
Fig1: Western blot analysis of TrkA+B+C on different lysates using anti-TrkA+B+C antibody at 1/1,000 dilution.; Positive control:; Lane 1: Rat brain; Lane 2: Mouse brain
Fig2: ICC staining TrkA+B+C in N2A cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Fig3: ICC staining TrkA+B+C in SH-SY-5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Fig4: Immunohistochemical analysis of paraffin-embedded mouse liver tissue using anti-TrkA+B+C antibody. Counter stained with hematoxylin.
Fig5: Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-TrkA+B+C antibody. Counter stained with hematoxylin.
- Background
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References
- Tatematsu T et al. Investigation of neurotrophic tyrosine kinase receptor 1 fusions and neurotrophic tyrosine kinase receptor family expression in non-small-cell lung cancer and sensitivity to AZD7451 in vitro. Mol Clin Oncol 2:725-730 (2014).
- Zhao T et al. Levo-tetrahydropalmatine retards the growth of ectopic endometrial implants and alleviates generalized hyperalgesia in experimentally induced endometriosis in rats. Reprod Sci 18:28-45 (2011).
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