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  • Anti-NTH1 Rabbit antibody

Anti-NTH1 Rabbit antibody

Cat.#: 168970

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Special Price 441.3 USD

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Product Information

  • Product Name
    Anti-NTH1 Rabbit antibody
  • Documents
  • Description
    NTH1 Rabbit monoclonal antibody
  • Tested applications
    WB, ICC/IF
  • Species reactivity
    Human, Mouse, Rat
  • Alternative names
    FAP3; NTH1; OCTS3; hNTH1 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: Recombinant protein of human NTH1
  • Clonality
    Monoclonal antibody
  • Formulation
    Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
  • Storage instructions
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze / thaw cycle.
  • Applications

    WB: 1/1000

    ICC/IF: 1/20

  • Validations

    Western blot detection of NTH1 in K562,Hela cell lysates using NTH1 Rabbit mAb(1:1000 diluted).Predicted band size:34kDa.Observed band size:34kDa.

    Western blot detection of NTH1 in K562,Hela cell lysates using NTH1 Rabbit mAb(1:1000 diluted).Predicted band size:34kDa.Observed band size:34kDa.

  • Background
    Swiss-Prot Acc.P78549.Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. Has also 8-oxo-7,8-dihydroguanine (8-oxoG) DNA glycosylase activity. Acts preferentially on DNA damage opposite guanine residues in DNA. Is able to process lesions in nucleosomes without requiring or inducing nucleosome disruption.
  • References

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"