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Product Name
Anti-NRF1 (9E6) Mouse antibody
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Description
NRF1 (9E6) Mouse monoclonal antibody
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Tested applications
WB
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Species reactivity
Human
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Alternative names
alpha pal;alpha palindromic binding protein;Alpha palindromic-binding protein;Alpha-pal; locus control region factor 1;NFE2 related factor 1;NRF-1;Nrf1;NRF1_HUMAN;Nuclear respiratory factor 1;transcription factor 11. antibody
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Isotype
IgG2a
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Preparation
Antigen: Purified recombinant human NRF1 protein fragments expressed in E.coli
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Clonality
Monoclonal
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Formulation
Purified mouse monoclonal in PBS(pH 7.4)containing with 0.02% sodium azide 50% glycerol 0.1%BSA.
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Storage instructions
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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Applications
WB: 1/1000
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Validations
Western blot detection of NRF1 in Hela,K562,CEM and U2OS cell lysates using TCF11/NRF1 mouse mAb (1:1000 diluted).Predicted band size:67KDa.Observed band size:72KDa.
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Background
Swiss-Prot Acc.Q16656.Transcription factor that activates the expression of the EIF2S1 (EIF2-alpha) gene. Links the transcriptional modulation of key metabolic genes to cellular growth and development. Implicated in the control of nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"