Anti-MSH6 Rabbit antibody

Cat.#: 167582

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Special Price 247.7 USD

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Product Information

  • Product Name
    Anti-MSH6 Rabbit antibody
  • Documents
  • Description
    MSH6 Rabbit monoclonal antibody
  • Tested applications
    WB, IHC-P, ICC/IF, FC, IP
  • Species reactivity
    Human
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: A synthetic peptide of human MSH6
  • Clonality
    Monoclonal
  • Formulation
    50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA
  • Storage instructions
    Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Applications

    WB: 1/1000

    IHC: 1/200

    ICC/IF: 1/20

    FC: 1/100

    IP: 1/20

  • Validations

    Western blot detection of MSH6 in A549,MCF-7,U251,C2C12 cell lysates using MSH6 Rabbit mAb(1:1000 diluted).Predicted band size:163kDa.Observed band size:163kDa.

    Western blot detection of MSH6 in A549,MCF-7,U251,C2C12 cell lysates using MSH6 Rabbit mAb(1:1000 diluted).Predicted band size:163kDa.Observed band size:163kDa.

  • Background
    This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described. [provided by RefSeq, Jul 2013]

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"