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Product Name
Anti-Metabotropic Glutamate Receptor 2/MGLUR2 Rabbit antibody
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Description
Metabotropic Glutamate Receptor 2/MGLUR2 Rabbit polyclonal antibody
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Tested applications
WB, IHC-P, ICC/IF, FC
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Species reactivity
Human, Mouse, Rat
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Alternative names
GLUR2; mGlu2; GPRC1B; MGLUR2 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide of human Metabotropic Glutamate Receptor 2
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Clonality
Polyclonal
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Formulation
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage instructions
Store at -20°C. Stable for 12 months from date of receipt.
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Applications
WB: 1/2000-1/10000
IHC: 1/50
ICC/IF: 1/50
FC: 1/20
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Validations
Western blot detection of Metabotropic Glutamate Receptor 2 in K562,Hela cell lysates using Metabotropic Glutamate Receptor 2 Rabbit pAb(1:1000 diluted).Predicted band size:99kDa.Observed band size:99kDa.
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Background
Swiss-Prot Acc.Q14416.G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"