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  • Anti-MCM7 Rabbit antibody

Anti-MCM7 Rabbit antibody

Cat.#: 168893

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Special Price 441.3 USD

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Product Information

  • Product Name
    Anti-MCM7 Rabbit antibody
  • Documents
  • Description
    MCM7 Rabbit monoclonal antibody
  • Tested applications
    WB, ICC/IF, FC
  • Species reactivity
    Human
  • Alternative names
    MCM2; CDC47; P85MCM; P1CDC47; PNAS146; PPP1R104; P1.1-MCM3 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: A synthetic peptide of human MCM7
  • Clonality
    Monoclonal antibody
  • Formulation
    Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
  • Storage instructions
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze / thaw cycle.
  • Applications

    1:1000

    1:20-1:50

    1:20

  • Validations

    Western blot detection of MCM7 in K562,C6,3T3,Hela cell lysates using MCM7 Rabbit mAb(1:1000 diluted).Predicted band size:81kDa.Observed band size:81kDa.

    Western blot detection of MCM7 in K562,C6,3T3,Hela cell lysates using MCM7 Rabbit mAb(1:1000 diluted).Predicted band size:81kDa.Observed band size:81kDa.

  • Background
    Swiss-Prot Acc.P33993.Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for S-phase checkpoint activation upon UV-induced damage.
  • References

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"