-
Product Name
Anti-M6PR Rabbit antibody
- Documents
-
Description
M6PR Rabbit polyclonal antibody
-
Tested applications
WB, IHC-P, ICC/IF, IP, FC
-
Species reactivity
Human, Mouse, Rat
-
Isotype
Rabbit IgG
-
Preparation
Antigen: A synthesized peptide derived from human M6PR
-
Clonality
Polyclonal
-
Formulation
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
-
Storage instructions
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
-
Applications
WB: 1/5000-1/20000
IHC: 1/50-1/200
ICC/IF: 1/50-1/200
IP: 1/30
FC: 1/100
-
Validations
Western blot analysis of extracts of M6PR expression in Jurkat cell lysate.
Immunohistochemical analysis of paraffin-embedded human colon, using M6PR Antibody.
-
Background
Swiss-Prot Acc.P11717.Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. Acts as a positive regulator of T-cell coactivation, by binding DPP4.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"