Anti-LILRB2 / ILT4 / LIR-2 antibody

Cat.#: 100117

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Product Information

  • Product Name
    Anti-LILRB2 / ILT4 / LIR-2 antibody
  • Documents
  • Description
    Mouse monoclonal to LILRB2 / ILT4 / LIR-2
  • Tested applications
    FCM
  • Species reactivity
    Human LILRB2 / ILT4 / LIR-2
  • Alternative names
    LILRB2 antibody; LIR2 antibody; LIR-2 antibody; member 6 antibody; MIR10 antibody; MIR-10 antibody; monocyte/macrophage immunoglobulin-like receptor 10 antibody; subfamily A (with TM domain) antibody; XXbac-BCX105G6.12-005 antibody; leukocyte immunoglobulin-like receptor antibody; subfamily B (with TM and ITIM domains) antibody; member 2 antibody; CD85 antigen-like family member D antibody; CD85D antibody; eukocyte immunoglobulin-like receptor antibody; Ig-like transcript 4 antibody; ILT4 antibody; ILT-4 antibody; immunoglobulin-like transcript 4 antibody; leukocyte immunoglobulin-like receptor 2 antibody; leukocyte immunoglobulin-like receptor subfamily B member 2 antibody; leukocyte immunoglobulin-like receptor subfamily B member 2 soluble isoform antibody; LILRA6 antibody
  • Immunogen
  • Isotype
    Mouse IgG2b
  • Preparation
    This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human LILRB2 / ILT4 / LIR-2 (rh LILRB2 / ILT4 / LIR-2; AAH36827.1; Met1-Val461) and conjugated with PE under optimum conditions, the unreacted PE was removed.
  • Clonality
    Monoclonal
  • Formulation
    Aqueous solution containing 0.5% BSA and 0.09% sodium azide
  • Storage instructions
    This antibody is stable for 12 months from date of receipt when stored at 2℃-8℃. Protected from prolonged exposure to light. Do not freeze !
    Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.
  • Applications
    FCM
  • Validations

    LILRB2 / ILT4 / LIR-2 Antibody, Mouse MAb, Flow Cytometry

    LILRB2 / ILT4 / LIR-2 Antibody, Mouse MAb, Flow Cytometry

    Flow cytometric analysis of Human LILRB2(CD85d) expression on human whole blood monocytes. Cells were stained with PE-conjugated anti-Human LILRB2(CD85d). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable monocytes.

  • Background
    ILT4, also known as LILRB2, is a member of the the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). ILT4 gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family. Multiple transcript variants encoding different isoforms have been found for ILT4 gene. ILT4 is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity.
  • References

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"