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Product Name
Anti-Leptin (5C11) Mouse antibody
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Description
Leptin (5C11) Mouse monoclonal antibody
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Tested applications
ELISA
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Species reactivity
Human
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Alternative names
FLJ94114; LEP; LEP_HUMAN; LEPD; Leptin (murine obesity homolog); Leptin (obesity homolog antibody; mouse); Leptin; Leptin Murine Obesity Homolog; Leptin Precursor Obesity Factor; OB; Obese Protein; Obese antibody; mouse antibody; homolog of; Obesity; Obesity factor; Obesity factor; antibody
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Isotype
Mouse IgG2a
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Preparation
Antigen: Purified recombinant full length of human Leptin protein expressed in E.coli.
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Clonality
Monoclonal
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Formulation
Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.03% Proclin300 and 50% glycerol.
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Storage instructions
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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Validations
Indirect ELISA assay for anti-Leptin mouse mAb.Antigen coating concentration: 4ug/ml.
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Background
Swiss-Prot Acc.P41159.This gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"