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Product Name
Anti-ITPA Rabbit antibody
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Description
ITPA Rabbit monoclonal antibody
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Tested applications
WB, IHC-P
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Species reactivity
Human
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Alternative names
My049; ITPase; NTPase; C20orf37; dJ794I6.3; HLC14-06-P antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide of human Inosine triphosphate pyrophosphatase
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Clonality
Monoclonal
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Formulation
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage instructions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze / thaw cycle.
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Applications
1:1000-1:5000
1:20-1:50
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Validations
Western blot detection of ITPA in Hela cell lysates using ITPA Rabbit mAb(1:1000 diluted).Predicted band size:22kDa.Observed band size:22kDa.
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Background
Swiss-Prot Acc.Q9BY32.Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"