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Product Name
Anti-ICAM1 Rabbit antibody
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Description
ICAM1 Rabbit polyclonal antibody
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Tested applications
WB, IHC-P, FC, IP
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Species reactivity
Human
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Alternative names
BB2; CD54; P3.58 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: Recombinant protein of human ICAM1
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Clonality
Polyclonal
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Formulation
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage instructions
Store at -20°C. Stable for 12 months from date of receipt.
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Applications
WB: 1/1000
IHC: 1/50
FC: 1/20-1/100
IP: 1/20
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Validations
Western blot detection of ICAM1 in K562,Hela cell lysates using ICAM1 Rabbit pAb(1:1000 diluted).Predicted band size:58kDa.Observed band size:89,92kDa.
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Background
Swiss-Prot Acc.P05362.ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"