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Product Name
Anti-HtrA2/Omi (8G11) Mouse antibody
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Description
HtrA2/Omi (8G11) Mouse monoclonal antibody
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Tested applications
WB, IP
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Species reactivity
Human
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Alternative names
High temperature requirement protein A2;HTRA 2;HtrA like serine protease;HtrA serine peptidase 2;HtrA antibody; E. coli antibody; homolog of antibody; 2;HtrA2;HTRA2_HUMAN;mitochondrial;Omi stress regulated endoprotease;Omi stress-regulated endoprotease;PARK 13;PARK13;Protease serin antibody
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Isotype
Mouse IgG1
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Preparation
Antigen: Recombinant human HtrA2/Omi protein.
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Clonality
Monoclonal
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Formulation
Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.03% Proclin300 and 50% glycerol.
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Storage instructions
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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Applications
WB: 1/500
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Validations
Western blot detection of HtrA2/Omi in 293T cell lysates using HtrA2/Omi mouse mAb(dilution 1:500).Predicted band size:49kDa.Observed band size:36kDa.
Immunoprecipitation analysis of Hela cell lysates using HtrA2/Omi mouse mAb.
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Background
Swiss-Prot Acc.O43464.High temperature requirement protein A2 (HtrA2)/Omi is a serine protease with homology to the E. coli HtrA protein (DegP) and is thought to be involved in apoptosis and stress-induced degradation of misfolded proteins. While HtrA2 was orignally identified to be present in either the nucleus or endoplasmic reticulum, subsequent studies have shown that it localizes in mitochondria and is released during apoptosis.
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