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Product Name
Anti-Hexokinase II (1E8) Mouse antibody
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Description
Hexokinase II (1E8) Mouse monoclonal antibody
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Tested applications
WB
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Species reactivity
Rat, Mouse, Monkey
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Alternative names
DKFZp686M1669;Hexokinase 2;Hexokinase 2 muscle;Hexokinase type II;Hexokinase-2;HK 2;HK II;HK2;HKII;HxK 2;HxK2;HXK2_HUMAN;Muscle form hexokinase. antibody
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Isotype
Mouse IgG1
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Preparation
Antigen: Recombinant human Hexokinase II protein.
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Clonality
Monoclonal
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Formulation
Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.03% Proclin300 and 50% glycerol.
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Storage instructions
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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Applications
WB: 1/500
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Validations
Western blot detection of Hexokinase II in 3tT3,COS7 and C6 cell lysates using Hexokinase II mouse mAb(dilution 1:500).Predicted band size:102kDa.Observed band size:102kDa.
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Background
Swiss-Prot Acc.P52789.Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"