Anti-HDAC4 (4A3) Mouse antibody

Cat.#: 168400

Special Price 123.9 USD

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Product Information

  • Product Name
    Anti-HDAC4 (4A3) Mouse antibody
  • Documents
  • Description
    HDAC4 (4A3) Mouse monoclonal antibody
  • Tested applications
    WB, IP
  • Species reactivity
    Human, Mouse, Rat, Monkey
  • Alternative names
    EC 3.5.1.98;HA6116;HD 4;HD4;HDAC 4;HDAC A;HDAC4;HDAC4_HUMAN;HDACA;Histone Deacetylase 4; Histone Deacetylase A;KIAA0288. antibody
  • Isotype
    Mouse IgG2a
  • Preparation
    Antigen: Purified recombinant human HDAC4 protein fragments expressed in E.coli
  • Clonality
    Monoclonal
  • Formulation
    Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4 150 mM NaCl) with 0.02% sodium azide 50% glycerol
  • Storage instructions
    Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Applications

    WB: 1/1000

  • Validations

    Western blot detection of HDAC4 in Jurkat,Hela and K562 cell lysates using HDAC4 mouse mAb (1:1000 diluted).Predicted band size: 140KDa.Observed band size: 140KDa.

    Western blot detection of HDAC4 in Jurkat,Hela and K562 cell lysates using HDAC4 mouse mAb (1:1000 diluted).Predicted band size: 140KDa.Observed band size: 140KDa.

    Immunoprecipitation analysis of Hela cell lysates using HDAC4 mouse mAb.

    Immunoprecipitation analysis of Hela cell lysates using HDAC4 mouse mAb.

    Western blot detection of HDAC4 in C2C12,3T3,K562,Jurkat and Hela cell lysates using HDAC4 mouse mAb(dilution 1:1000).Predicted band size:140kDa.Observed band size:140kDa.

    Western blot detection of HDAC4 in C2C12,3T3,K562,Jurkat and Hela cell lysates using HDAC4 mouse mAb(dilution 1:1000).Predicted band size:140kDa.Observed band size:140kDa.

  • Background
    Swiss-Prot Acc.P56524.Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"