Anti-GDF11 antibody

Cat.#: 176705

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Product Information

  • Product Name
    Anti-GDF11 antibody
  • Documents
  • Description
    Rabbit polyclonal antibody to GDF11
  • Tested applications
    WB, ICC, IHC-P, FC
  • Species reactivity
    Human, Mouse, Rat
  • Alternative names
    VHO antibody; BMP11 antibody; BMP-11 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antigen of this antibody was recombinant protein
  • Clonality
    Polyclonal
  • Formulation
    Liquid, 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage instructions
    Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
  • Applications

    ICC: 1:50-1:200

    IHC-P: 1:50-1:200

    FC: 1:50-1:100

    WB: 1:500

  • Validations

    Fig1: Immunocytochemical staining of Hela cells using anti-BMP11 rabbit polyclonal antibody.

    Fig1: Immunocytochemical staining of Hela cells using anti-BMP11 rabbit polyclonal antibody.

    Fig2: Immunocytochemical staining of SW480 cells using anti-BMP11 rabbit polyclonal antibody.

    Fig2: Immunocytochemical staining of SW480 cells using anti-BMP11 rabbit polyclonal antibody.

    Fig3: Immunohistochemical analysis of paraffin- embedded human colon cancer tissue using anti-BMP11 rabbit polyclonal antibody.

    Fig3: Immunohistochemical analysis of paraffin- embedded human colon cancer tissue using anti-BMP11 rabbit polyclonal antibody.

    Fig4: Immunohistochemical analysis of paraffin- embedded mouse brain tissue using anti-BMP11 rabbit polyclonal antibody.

    Fig4: Immunohistochemical analysis of paraffin- embedded mouse brain tissue using anti-BMP11 rabbit polyclonal antibody.

    Fig5: Flow cytometric analysis of HepG2 cells with BMP11 antibody at 1/100 dilution (blue) compared with an unlabelled control (cells without incubation with primary antibody; red). Alexa Fluor 488-conjugated Goat anti rabbit IgG was used as the secondary antibody.

    Fig5: Flow cytometric analysis of HepG2 cells with BMP11 antibody at 1/100 dilution (blue) compared with an unlabelled control (cells without incubation with primary antibody; red). Alexa Fluor 488-conjugated Goat anti rabbit IgG was used as the secondary antibody.

  • Background
  • References
    • Poggioli T et al. Circulating Growth Differentiation Factor 11/8 Levels Decline with Age. Circ Res 118(1):29-37 (2015).
    • Egerman MA et al. GDF11 Increases with Age and Inhibits Skeletal Muscle Regeneration. Cell Metab 22:164-74 (2015).

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"