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Product Name
Anti-FGFR2 antibody
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Description
Mouse monoclonal antibody to FGFR2
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Tested applications
WB, ICC, FC
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Species reactivity
Human, Mouse
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Alternative names
BEK antibody; JWS antibody; BBDS antibody; CEK3 antibody; CFD1 antibody; ECT1 antibody; KGFR antibody; TK14 antibody; TK25 antibody; BFR-1 antibody; CD332 antibody; K-SAM antibody
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Isotype
Mouse IgG1
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Preparation
This antigen of this antibody was recombinant protein
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Clonality
Monoclonal
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Formulation
Liquid, 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Storage instructions
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
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Applications
ICC: 1:50 WB: 1:2000
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Validations
Fig1: Western blot analysis on K562 cell lysates using anti-FGFR2 mouse mAb.
Fig2: ICC staining FGFR2 in MCF-7 cells (red). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
- Background
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References
- Fibroblast growth factor signalling: from development to cancer. Turner N., Grose R. Nat. Rev. Cancer 10:116-129(2010)
- FGFR2 abnormalities underlie a spectrum of bone, skin, and cancer pathologies. Katoh M. J. Invest. Dermatol. 129:1861-1867(2009)
- Cbl-mediated degradation of Lyn and Fyn induced by constitutive fibroblast growth factor receptor-2 activation supports osteoblast differentiation. Kaabeche K., Lemonnier J., Le Mee S., Caverzasio J., Marie P.J. J. Biol. Chem. 279:36259-36267(2004)
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"