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Anti-FGFR2 antibody

Cat.#: 175098

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Special Price 241.9 USD

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Product Information

  • Product Name
    Anti-FGFR2 antibody
  • Documents
  • Description
    Mouse monoclonal antibody to FGFR2
  • Tested applications
    WB, ICC, IHC-P
  • Species reactivity
    Human, Mouse
  • Alternative names
    BEK antibody; JWS antibody; BBDS antibody; CEK3 antibody; CFD1 antibody; ECT1 antibody; KGFR antibody; TK14 antibody; TK25 antibody; BFR-1 antibody; CD332 antibody; K-SAM antibody
  • Isotype
    Mouse IgG1
  • Preparation
    This antigen of this antibody was recombinant protein
  • Clonality
    Monoclonal
  • Formulation
    Liquid, 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage instructions
    Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
  • Applications

    WB: 1:500

    ICC: 1:100-1:200

    IHC-P: 1:100-1:200

  • Validations

    Fig1: Western blot analysis of FGFR2 on different cell lysates using anti-FGFR2 antibody at 1/500 dilution.; Positive control:; Lane 1: MCF-7; Lane 2: K562; Lane 3: Hela; Lane 4: HepG2; Lane 5: A431; Lane 6: A549; Lane 7: NIH/3T3; Lane 8: Jurkat; Lane 9: Mouse brain

    Fig1: Western blot analysis of FGFR2 on different cell lysates using anti-FGFR2 antibody at 1/500 dilution.; Positive control:; Lane 1: MCF-7; Lane 2: K562; Lane 3: Hela; Lane 4: HepG2; Lane 5: A431; Lane 6: A549; Lane 7: NIH/3T3; Lane 8: Jurkat; Lane 9: Mouse brain

    Fig2: ICC staining of FGFR2 in MCF-7 cells (red). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

    Fig2: ICC staining of FGFR2 in MCF-7 cells (red). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

    Fig3: ICC staining of FGFR2 in Ags cells (red). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

    Fig3: ICC staining of FGFR2 in Ags cells (red). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

    Fig4: Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using anti-FGFR2 antibody. Counter stained with hematoxylin.

    Fig4: Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using anti-FGFR2 antibody. Counter stained with hematoxylin.

    Fig5: Immunohistochemical analysis of paraffin-embedded human stomach carcinoma tissue using anti-FGFR2 antibody. Counter stained with hematoxylin.

    Fig5: Immunohistochemical analysis of paraffin-embedded human stomach carcinoma tissue using anti-FGFR2 antibody. Counter stained with hematoxylin.

    Fig6: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-FGFR2 antibody. Counter stained with hematoxylin.

    Fig6: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-FGFR2 antibody. Counter stained with hematoxylin.

  • Background
    P21802
  • References
    • Fibroblast growth factor signalling: from development to cancer. Turner N., Grose R. Nat. Rev. Cancer 10:116-129(2010)
    • FGFR2 abnormalities underlie a spectrum of bone, skin, and cancer pathologies. Katoh M. J. Invest. Dermatol. 129:1861-1867(2009)
    • Cbl-mediated degradation of Lyn and Fyn induced by constitutive fibroblast growth factor receptor-2 activation supports osteoblast differentiation. Kaabeche K., Lemonnier J., Le Mee S., Caverzasio J., Marie P.J. J. Biol. Chem. 279:36259-36267(2004)

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"