-
Product Name
Anti-DR5 (6F6) Mouse antibody
- Documents
-
Description
DR5 (6F6) Mouse monoclonal antibody
-
Tested applications
WB
-
Species reactivity
Human
-
Alternative names
Fas like protein ;Apoptosis inducing protein TRICK2A/2B ;Apoptosis inducing receptor TRAIL R2 ;CD 262 ;CD262 ;CD262 antigen ;Cytotoxic TRAIL receptor 2 ;Death domain containing receptor for TRAIL/Apo 2L ;Death domain containing receptor for TRAIL/Apo2L ;D antibody
-
Isotype
Mouse IgG2b
-
Preparation
Antigen: Purified recombinant human DR5 protein fragments expressed in E.coli.
-
Clonality
Monoclonal
-
Formulation
Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.02% sodium azide and 50% glycerol.
-
Storage instructions
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
-
Applications
WB: 1/1000;Other 1/2000
-
Validations
Western blot detection of DR5 in SW480,K562,HCT116 and Hela cell lysates using DR5 mouse mAb (1:1000 diluted).Predicted band size:40/48KDa.Observed band size:40/48KDa.
Western blot detection of DR5 in MCF-7 and T47D cell lysates using DR5 mouse mAb (1:2000 diluted).Predicted band size:40/48KDa.Observed band size:40/48KDa.
-
Background
Swiss-Prot Acc.O14763.Plays an important role in the regulation of apoptosis in various physiological systems. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"