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Product Name
Anti-Cyclin H (4E11) Mouse antibody
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Description
Cyclin H (4E11) Mouse monoclonal antibody
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Tested applications
WB, IP
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Species reactivity
Human
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Alternative names
6330408H09Rik;AI661354;AV102684;AW538719;CAK;CAK complex subunit;ccnh;CCNH_HUMAN;CDK activating kinase;CDK activating kinase complex subunit;Cyclin dependent kinase activating kinase;cyclin dependent kinase activating kinase complex subunit;Cyclin H; Cycl antibody
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Isotype
IgG2b
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Preparation
Antigen: Purified recombinant human Cyclin H protein fragments expressed in E.coli.
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Clonality
Monoclonal
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Formulation
Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4 150 mM NaCl) with 0.02% sodium azide 50% glycerol
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Storage instructions
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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Applications
WB: 1/1000
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Validations
Immunoprecipitation analysis of Hela cell lysates using Cyclin H mouse mAb.
Western blot detection of Cyclin H in Jurkat,K562 and A431 cell lysates using Cyclin H mouse mAb (1:1000 diluted).Predicted band size: 38KDa.Observed band size: 38KDa.
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Background
Swiss-Prot Acc.P51946.Cyclin H belongs to a conserved cyclin family that plays a critical role in the regulation of cell cycle dependent kinases (CDKs) necessary for cell cycle progression. In general, the activity of CDKs requires the binding of appropriate cyclins as well as phosphorylation driven by Cdk-activating kinase (CAK). Involved in cell cycle control and in RNA transcription by RNA polymerase II.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"