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Product Name
Anti-Cryptochrome I/CRY1 (2D6) Mouse antibody
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Description
Cryptochrome I/CRY1 (2D6) Mouse monoclonal antibody
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Tested applications
WB
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Species reactivity
Human, Mouse, Rat, Monkey
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Alternative names
Damage specific DNA binding protein 1;Damage-specific DNA-binding protein 1;DDB 1;DDB p127 subunit;Ddb1;DDB1_HUMAN;DDBa ;DNA damage binding protein 1;DNA damage-binding protein 1;DNA damage-binding protein a;HBV X-associated protein 1;UV damaged DNA bindi antibody
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Isotype
Mouse IgG2b
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Preparation
Antigen: Purified recombinant human DDB1 protein fragments expressed in E.coli.
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Clonality
Monoclonal
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Formulation
Ascites containing with 0.03% Proclin300 and 50% glycerol.
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Storage instructions
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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Applications
WB: 1/1000
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Validations
Western blot detection of DDB1 in Hela,MCF7,COS7,C6 and 3T3 cell lysates using DDB1 mouse mAb (1:1000 diluted),with Super ECL.Predicted band size:127KDa.Observed band size:127KDa.
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Background
Swiss-Prot Acc.Q16531.Required for DNA repair. Binds to DDB2 to form the UV-damaged DNA-binding protein complex (the UV-DDB complex). The UV-DDB complex may recognize UV-induced DNA damage and recruit proteins of the nucleotide excision repair pathway (the NER pathway) to initiate DNA repair.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"