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Product Name
Anti-CIRBP Rabbit antibody
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Description
CIRBP Rabbit polyclonal antibody
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Tested applications
WB, IHC-P, IP
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Species reactivity
Human
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Alternative names
CIRP antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: Recombinant protein of human CIRBP
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Clonality
Polyclonal
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Formulation
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage instructions
Store at -20°C. Stable for 12 months from date of receipt.
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Applications
WB: 1/1000
IHC: 1/200
IP: 1/20
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Validations
Western blot detection of CIRBP in Hela cell lysates using CIRBP Rabbit pAb(1:1000 diluted).Predicted band size:19kDa.Observed band size:19kDa.
Immunohistochemistry of CIRBP in paraffin-embedded Human breast cancer tissue using CIRBP Rabbit pAb at dilution 1/50
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Background
Swiss-Prot Acc.Q14011.Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor . Promotes assembly of stress granules (SGs), when overexpressed.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"