Anti-CIRBP Rabbit antibody

Cat.#: 166816

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Special Price 441.3 USD

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Product Information

  • Product Name
    Anti-CIRBP Rabbit antibody
  • Documents
  • Description
    CIRBP Rabbit polyclonal antibody
  • Tested applications
    WB, IHC-P, IP
  • Species reactivity
    Human
  • Alternative names
    CIRP antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: Recombinant protein of human CIRBP
  • Clonality
    Polyclonal
  • Formulation
    Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
  • Storage instructions
    Store at -20°C. Stable for 12 months from date of receipt.
  • Applications

    WB: 1/1000

    IHC: 1/200

    IP: 1/20

  • Validations

    Western blot detection of CIRBP in Hela cell lysates using CIRBP Rabbit pAb(1:1000 diluted).Predicted band size:19kDa.Observed band size:19kDa.

    Western blot detection of CIRBP in Hela cell lysates using CIRBP Rabbit pAb(1:1000 diluted).Predicted band size:19kDa.Observed band size:19kDa.

    Immunohistochemistry of CIRBP in paraffin-embedded Human breast cancer tissue using CIRBP Rabbit pAb at dilution 1/50

    Immunohistochemistry of CIRBP in paraffin-embedded Human breast cancer tissue using CIRBP Rabbit pAb at dilution 1/50

  • Background
    Swiss-Prot Acc.Q14011.Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor . Promotes assembly of stress granules (SGs), when overexpressed.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"