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Product Name
Anti-Ccnd1 antibody
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Description
Rabbit polyclonal antibody to Ccnd1
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Tested applications
WB, IHC-P
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Species reactivity
Human, Mouse, Rat
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Alternative names
PR antibody; cD1 antibody; Cyl- antibody; bcl- antibody; CycD1 antibody; Cyl-1 antibody; PRAD1 antibody; bcl-1 antibody; AI327039 antibody
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Isotype
Rabbit IgG
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Preparation
This antigen of this antibody was peptide
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Clonality
Polyclonal
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Formulation
Liquid, 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Storage instructions
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
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Applications
WB: 1:2,000-1:5,000
IHC-P: 1:200
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Validations
Fig1: Western blot analysis of cyclin D1 on mouse brain tissue lysates using anti-Cyclin D1 antibody at 1/5000 dilution.; Positive control: mouse brain
Fig2: Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Cyclin D1 antibody. Counter stained with hematoxylin.
Fig3: Immunohistochemical analysis of paraffin-embedded human liver carcinoma tissue using anti-Cyclin D1 antibody. Counter stained with hematoxylin.
- Background
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References
- Zinc finger transcription factor INSM1 interrupts cyclin D1 and CDK4 binding and induces cell cycle arrest. Zhang T., Liu W.D., Saunee N.A., Breslin M.B., Lan M.S. J. Biol. Chem. 284:5574-5581(2008)
- F-box protein FBXO31 mediates cyclin D1 degradation to induce G1 arrest after DNA damage. Santra M.K., Wajapeyee N., Green M.R. Nature 459:722-725(2008)
- An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. Bian Y., Song C., Cheng K., Dong M., Wang F., Huang J., Sun D., Wang L., Ye M., Zou H.J. Proteomics 96:253-262(2013)
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"