Anti-Caspase-6 Rabbit antibody

Cat.#: 167775

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Product Information

  • Product Name
    Anti-Caspase-6 Rabbit antibody
  • Documents
  • Description
    Caspase-6 Rabbit monoclonal antibody
  • Tested applications
    WB, IHC-P, ICC/IF, FC
  • Species reactivity
    Human, Mouse
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: A synthetic peptide of human Caspase-6
  • Clonality
    Monoclonal
  • Formulation
    50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA
  • Storage instructions
    Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Applications

    WB: 1/1000

    IHC: 1/20

    ICC/IF: 1/20

    FC: 1/20

  • Validations

    Western blot detection of Caspase-6 in A549,MCF-7,U251,HL-60 cell lysates using Caspase-6 Rabbit mAb(1:1000 diluted).Predicted band size:33kDa.Observed band size:33kDa,11kDa(cleavage).

    Western blot detection of Caspase-6 in A549,MCF-7,U251,HL-60 cell lysates using Caspase-6 Rabbit mAb(1:1000 diluted).Predicted band size:33kDa.Observed band size:33kDa,11kDa(cleavage).

  • Background
    This gene encodes a member of the cysteine-aspartic acid protease (caspase) family of enzymes. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic acid residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Oct 2015]

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"