Anti-CaMKII alpha Rabbit antibody

Cat.#: 167166

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Product Information

  • Product Name
    Anti-CaMKII alpha Rabbit antibody
  • Documents
  • Description
    CaMKII alpha Rabbit polyclonal antibody
  • Tested applications
    WB, ICC/IF, FC
  • Species reactivity
    Human, Mouse, Rat
  • Alternative names
    CAMKA; MRD53; MRT63; CaMKIINalpha antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: A synthetic peptide of human CaMKII
  • Clonality
    Polyclonal
  • Formulation
    Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
  • Storage instructions
    Store at -20°C. Stable for 12 months from date of receipt.
  • Applications

    WB: 1/1000-1/2000

    ICC/IF: 1/20-1/100

    FC: 1/20-1/100

  • Validations

    Western blot detection of CaMKII alpha in Rat Brain,Hela cell lysates using CaMKII alpha Rabbit pAb(1:1000 diluted).Predicted band size:54kDa.Observed band size:54kDa.

    Western blot detection of CaMKII alpha in Rat Brain,Hela cell lysates using CaMKII alpha Rabbit pAb(1:1000 diluted).Predicted band size:54kDa.Observed band size:54kDa.

  • Background
    Swiss-Prot Acc.Q9UQM7.Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca2+/calmodulin-binding and autophosphorylation, and is involved in synaptic plasticity, neurotransmitter release and long-term potentiation. Member of the NMDAR signaling complex in excitatory synapses, it regulates NMDAR-dependent potentiation of the AMPAR and therefore excitatory synaptic transmission . Regulates dendritic spine development (PubMed:28130356). Also regulates the migration of developing neurons (PubMed:29100089). Phosphorylates the transcription factor FOXO3 to activate its transcriptional activity (PubMed:23805378).

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"